Abel Xavier's long throw from the right is flicked on at the near post by Emile Heskey, and El-Hadji Diouf leaps above the Saints defence to power home a header at the Kop end.
Pre-Southampton Press Conference with Gerard Houllier at Melwood
New Anfield Number Nine El-Hadji Diouf was the star of the show with two goals to sink Southampton. Danny Murphy added a late penalty but all the talk was about Diouf scoring on his Anfield Premiership debut.
Steven Gerrard plays a great ball out to Emile Heskey on the left wing. Heskey runs at the Saints defence and crosses to the back post for El-Hadji Diouf to put Liverpool 1-0 up.
Substitute Bruno Cheyrou is fouled in the box and Danny Murphy makes it 3-0 from the penalty spot.
Watch Gerard Houllier's verdict on Liverpool's 3-0 win over Southampton at Anfield.